Article
Viral peptide specific induction of MHC class II expression by murine T cell clones.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 1996
Thomas D B, Smith C A, Graham C M
Abstract excerpt
We report that I-Ab-restricted T cell clones, elicited by influenza infection of C57BL/10 mice and specific for the hemagglutinin peptide HA1 186-205, express class II. They respond to peptide stimulation by IL release (IL-3 or IFN-gamma) without a requirement for APC but do not proliferate. Moreover, surface expression of class II requires de novo synthesis in the presence of the stimulatory peptide and is...
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