Article
Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide.
Proceedings of the National Academy of Sciences of the United States of America - 31 Jul 2001
Viret C, He X, Janeway C A
Abstract excerpt
The Y-Ae mAb and the 1H3.1 alphabeta T cell antigen receptor (TCR) are both specific for the I-Ealpha52-68 peptide bound to the I-A(b) major histocompatibility complex (MHC) class II molecule. Antigen-presenting cells (APCs) from I-A(b+) mice with a natural or transgenic (Tg) I-Ealpha chain activ...
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