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Article

Replication activity of JC virus large T antigen phosphorylation and zinc finger domain mutants.

Journal of neurovirology - 1 Apr 1996

Swenson J J, Trowbridge P W, Frisque R J

Abstract excerpt

The replication potential of the human polyomavirus JC virus (JCV) relative to that of the related monkey virus SV40 is limited, in part, by differences in the multifunctional T antigen (T Ag). Earlier genetic analyses of the SV40 T protein indicated that specific phosphorylation sites and a zinc finger motif are involved in the regulation of viral replication. The JCV and SV40 T Ags differ with respect to...

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PMID: 8799199
DOI: 10.3109/13550289609146541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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