Article
Replication activity of JC virus large T antigen phosphorylation and zinc finger domain mutants.
Journal of neurovirology - 1 Apr 1996
Swenson J J, Trowbridge P W, Frisque R J
Abstract excerpt
The replication potential of the human polyomavirus JC virus (JCV) relative to that of the related monkey virus SV40 is limited, in part, by differences in the multifunctional T antigen (T Ag). Earlier genetic analyses of the SV40 T protein indicated that specific phosphorylation sites and a zinc...
Topics
- Amino Acid Sequence
- Antigens, Polyomavirus Transforming
- Antigens, Viral, Tumor
- Cell Transformation, Viral
- Cells, Cultured
- DNA, Viral
- Genotype
- Humans
- JC Virus
- Molecular Sequence Data
- Mutagenesis
- Phosphorylation
- Protein Structure, Tertiary
- Replication Origin
- Virus Replication
- Zinc Fingers