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Article

Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity.

The Journal of biological chemistry - 5 Jul 1996

Arroyo M P, Downey K M, So A G, Wang T S

Abstract excerpt

We introduced nine site-directed mutations into seven conserved fission yeast proliferative cell nuclear antigen (PCNA) residues, Leu2, Asp63, Arg64, Gly69, Gln201, Glu259, and Glu260, either as single or as double mutants. Both the recombinant wild type and mutant PCNAs were able to form homotrimers in solution and to sustain growth of a null pcna strain (Deltapcna). Wild type Schizosaccharomyces pombe PCNA and...

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Source

Identifiers

PMID: 8663159
DOI: 10.1074/jbc.271.27.15971

Genes

PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity.PMID 8663159Read ↗

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Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis.Semantic proximity Read ↗

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