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Small tumor antigen of polyomaviruses: Role in viral life cycle and cell transformation

16 Nov 2007

Abstract excerpt

The regulatory proteins of polyomaviruses, including small and large T antigens, play important roles, not only in the viral life cycle but also in virus-induced cell transformation. Unlike many other tumor viruses, the transforming proteins of polyomaviruses have no cellular homologs but rather exert their effects mostly by interacting with cellular proteins that control fundamental processes in the regulation...

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PMID: 18022798
DOI: 10.1002/jcp.21326

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