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Article

Dual leucine zipper-bearing kinase (DLK) activates p46SAPK and p38mapk but not ERK2.

The Journal of biological chemistry - 4 Oct 1996

Fan G, Merritt S E, Kortenjann M, Shaw P E, Holzman L B

Abstract excerpt

Because the catalytic domain of dual leucine zipper-bearing kinase (DLK) bears sequence similarity to members of the mitogen-activated protein (MAP) kinase kinase kinase subfamily, this protein kinase was investigated for its ability to activate MAP kinase pathways. When transiently transfected and overexpressed in either COS 7 cells or NIH3T3 cells, wild type DLK potently activated p46(SAPK) (SAPK/JNK) but had...

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Identifiers

PMID: 8798750
DOI: 10.1074/jbc.271.40.24788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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