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Article

Identification of a specific domain responsible for JNK2alpha2 autophosphorylation.

The Journal of biological chemistry - 18 Mar 2005

Cui Jian, Holgado-Madruga Marina, Su Wanwen, Tsuiki Hiromasa, Wedegaertner Philip, Wong Albert J

Abstract excerpt

c-Jun N-terminal kinases (JNKs) are a group of mitogen-activated protein kinase family members that are important in regulating cell growth, proliferation, and apoptosis. Activation of the JNK pathway has been implicated in the formation of several human tumors. We have previously demonstrated that a 55-kDa JNK isoform is constitutively activated in 86% of human brain tumors and more recently demonstrated that...

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PMID: 15637069
DOI: 10.1074/jbc.M412165200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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