Article
Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression.
Molecular and cellular biology - 1 Jan 1999
Cacace A M, Michaud N R, Therrien M, Mathes K, Copeland T, Rubin G M, Morrison D K
Abstract excerpt
Genetic and biochemical studies have identified kinase suppressor of Ras (KSR) to be a conserved component of Ras-dependent signaling pathways. To better understand the role of KSR in signal transduction, we have initiated studies investigating the effect of phosphorylation and protein interactio...
Topics
- 14-3-3 Proteins
- 3T3 Cells
- Animals
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Line
- Cell Line, Transformed
- Drosophila melanogaster
- Mice
- Mutation
- Phosphorylation
- Protein Binding
- Protein Kinases
- Proteins