Article
Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2.
PloS one - 1 Jan 2011
Teng Allen C T, Al-Montashiri Naif A M, Cheng Brian L M, Lou Philip, Ozmizrak Pinar, Chen Hsiao-Huei, Stewart Alexandre F R
Abstract excerpt
BACKGROUND: Interferon regulatory factor 2 binding protein 2 (IRF2BP2) is a muscle-enriched transcription factor required to activate vascular endothelial growth factor-A (VEGFA) expression in muscle. IRF2BP2 is found in the nucleus of cardiac and skeletal muscle cells. During the process of skeletal muscle differentiation, some IRF2BP2 becomes relocated to the cytoplasm, although the functional significance of...
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