Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.

doi:10.1073/pnas.90.12.5554

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Article

Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 1993

Vogt T F, Jackson-Grusby L, Rush J, Leder P

Abstract excerpt

Mutations at the mouse limb deformity (ld) locus result in defects of growth and patterning of the limb and kidney during embryonic development. The gene responsible for this phenotype is large and complex, with the capacity to generate a number of alternatively spliced messenger RNA transcripts...

Topics

3T3 Cells
Alleles
Animals
Cell Line
Chromatography, Affinity
DNA
Electrophoresis, Polyacrylamide Gel
Extremities
Fetal Proteins
Formins
Heterozygote
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney

Limb Deformities, Congenital

Mice

Mice, Mutant Strains

Microfilament Proteins

Molecular Weight

Source

Open in PubMed Open full text

Identifiers

PMID: 8516300
DOI: 10.1073/pnas.90.12.5554
PMCID: PMC46759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8516300-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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