'Formins': proteins deduced from the alternative transcripts of the limb deformity gene.

doi:10.1038/346850a0

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Article

'Formins': proteins deduced from the alternative transcripts of the limb deformity gene.

Nature - 30 Aug 1990

Woychik R P, Maas R L, Zeller R, Vogt T F, Leder P

Abstract excerpt

Vertebrate limb formation is an evolutionarily conserved process programmed by an array of morphogenetic genes. As a result of transgene insertion, we previously identified a mutation at the mouse limb deformity (ld) locus that disrupts embryonic pattern formation, resulting in a reduction and fu...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
DNA
Exons
Extremities
Gene Expression
Limb Deformities, Congenital
Mice
Mice, Transgenic
Molecular Sequence Data
Morphogenesis
Mutation
Nuclear Proteins
Nucleic Acid Hybridization
Poly A

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