Article
Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: with respect to histological subtypes and stages.
Journal of gastroenterology and hepatology - 1 Mar 1998
Wu M S, Shun C T, Sheu J C, Wang H P, Wang J T, Lee W J, Chen C J, Wang T H, Lin J T
Abstract excerpt
Although the mechanism remains obscure, two histological subtypes of gastric carcinoma (GC), the diffuse and intestinal types, differ drastically in epidemiological, clinical, pathological and biological characteristics. We investigated whether the genetic alterations of several oncogenes and tumour suppressor genes could be correlated with the two histological subtypes. In 60 patients with GC, the overexpression...
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