Article
p21 expression and mutation in gastric carcinoma: analysis by immunohistochemistry and PCR-SSCP.
Journal of Korean medical science - 1 Oct 1998
Park Y E, Choi K C, Choi Y H
Abstract excerpt
p21 protein has been reported to be a critical downstream effector of p53 and a potent inhibitor of cyclin-dependent kinases. Thus, the p21 gene is thought to play a central role in tumor suppression. In this study we investigated p21 protein expression and mutation in gastric adenocarcinoma. A total of 76 primary gastric carcinoma specimens were immunohistochemically stained for p21 protein expression and...
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