Article
The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer.
Molecular medicine today - 1 Jan 1996
Soussi T
Abstract excerpt
The gene encoding the tumour suppressor protein p53 is one of the most commonly mutated genes in human cancers. Analysis of the mutational events that target the p53 gene has revealed evidence for both exogenous and endogenous mutational mechanisms. For example, the p53 mutational spectrum reveals evidence for a direct causal effect of ultraviolet radiation in skin cancer, of aflatoxin B1 in liver cancer and of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
