The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer.

doi:10.1016/1357-4310(96)88756-9

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Article

The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer.

Molecular medicine today - 1 Jan 1996

Soussi T

Abstract excerpt

The gene encoding the tumour suppressor protein p53 is one of the most commonly mutated genes in human cancers. Analysis of the mutational events that target the p53 gene has revealed evidence for both exogenous and endogenous mutational mechanisms. For example, the p53 mutational spectrum reveal...

Topics

Aflatoxin B1
Animals
Carcinogens
Carcinoma, Hepatocellular
Dinucleoside Phosphates
Genes, Tumor Suppressor
Genes, p53
Genetic Markers
Genome
Humans
Lung Neoplasms
Molecular Epidemiology
Mutation
Skin Neoplasms
Smoking
Ultraviolet Rays

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