Article
p53: at the crossroads of molecular carcinogenesis and molecular epidemiology.
The journal of investigative dermatology. Symposium proceedings - 1 Apr 1996
Harris C C
Abstract excerpt
The p53 tumor suppressor gene is frequently mutated in human cancer, including squamous cell carcinoma and basal cell carcinoma of the skin, but is rarely mutated in skin melanoma. The p53 mutation spectrum provides insight into both the etiology of human cancer and the functional regions of the...
Topics
- Animals
- Genes, Tumor Suppressor
- Genes, p53
- Genetic Predisposition to Disease
- Humans
- Mutation
- Neoplasms