Article
Cardiac and vascular effects of long-term losartan treatment in stroke-prone spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 1996
Gohlke P, Linz W, Schölkens B A, Wiemer G, Unger T
Abstract excerpt
In previous studies in stroke-prone spontaneously hypertensive rats (SHRSP), we demonstrated that early-onset, long-term angiotensin-converting enzyme inhibitor treatment improved cardiac function and metabolism and increased aortic cGMP content even at sub-antihypertensive doses. These effects c...
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