Article
Protective effects of valsartan and benazeprilat in salt-loaded stroke-prone spontaneously hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Oct 1998
Webb R L, Barclay B W, Navarrete A E, Wosu N J, Sahota P
Abstract excerpt
These experiments examined the effectiveness of chronic blockade of the renin angiotensin system with either valsartan or benazeprilat on survival, blood pressure and end-organ damage in salt-loaded stroke-prone SHR. Valsartan or benazeprilat given continuously by subcutaneous osmotic minipump beginning at 10.5 weeks of age lowered blood pressure, as determined by radiotelemetry, prevented proteinuria, prolonged...
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