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Article

Antihypertensive effect of biotin in stroke-prone spontaneously hypertensive rats.

The British journal of nutrition - 1 Apr 2008

Watanabe-Kamiyama Mari, Kamiyama Shin, Horiuchi Kimiko, Ohinata Kousaku, Shirakawa Hitoshi, Furukawa Yuji, Komai Michio

Abstract excerpt

Biotin is a member of the vitamin B-complex family. Biotin deficiency has been associated with hyperglycaemia and insulin resistance in animals and humans. In the present study, we investigated the pharmacological effects of biotin on hypertension in the stroke-prone spontaneously hypertensive rat (SHRSP) strain. We observed that long-term administration of biotin decreased systolic blood pressure in the SHRSP...

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PMID: 18179728
DOI: 10.1017/S0007114507841122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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