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Article

Losartan versus enalapril on cerebral edema and proteinuria in stroke-prone hypertensive rats.

American journal of hypertension - 1 Jan 2001

Blezer E L, Nicolay K, Koomans H A, Joles J A

Abstract excerpt

Stroke-prone spontaneously hypertensive rats (SHRSP), subjected to high NaCl, show severe hypertension, organ damage, and early death. Preventive treatment with angiotensin II type 1 (AT1) receptor antagonists is known to be effective. Previously, we found that angiotensin converting enzyme (ACE) inhibition could reduce cerebral edema when treatment was started after manifestation of either proteinuria or...

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Identifiers

PMID: 11206680
DOI: 10.1016/s0895-7061(00)01231-0

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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