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Article

Mutational analysis of the encephalomyocarditis virus primary cleavage.

Journal of virology - 1 Oct 1996

Hahn H, Palmenberg A C

Abstract excerpt

Sixteen substitution mutations of the conserved DvExNPGP sequence, implicated in cardiovirus and aphthovirus primary polyprotein cleavage, were created in encephalomyocarditis virus cDNA, expressed, and characterized for processing activity. Nearly all the mutations severely decreased the efficiency of the primary cleavage reaction during cell-free synthesis of viral precursors, indicating a stringent requirement...

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Source

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Identifiers

PMID: 8794329
DOI: 10.1128/JVI.70.10.6870-6875.1996
PMCID: PMC190735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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