Article
Identification of the nucleotide substitution that generates the fourth polymorphic site in human deoxyribonuclease I (DNase I).
Human genetics - 1 Oct 1996
Iida R, Yasuda T, Takeshita H, Tsubota E, Yuasa I, Nakajima T, Kishi K
Abstract excerpt
In addition to the three polymorphic sites responsible for protein polymorphism, a new polymorphic site has been identified in intron 7 of the human deoxyribonuclease I (DNase I) gene. Three phenotypes were observed on single-strand conformational polymorphism analysis of a 266-bp polymerase chai...
Topics
- Base Sequence
- DNA Primers
- Deoxyribonuclease I
- Exons
- Genotype
- Humans
- Introns
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational