Article
A novel 56-bp variable tandem repeat polymorphism in the human deoxyribonuclease I gene and its population data.
Legal medicine (Tokyo, Japan) - 1 Oct 2004
Yasuda Toshihiro, Iida Reiko, Ueki Misuzu, Tsukahara Tetsuya, Nakajima Tamiko, Kominato Yoshihiko, Takeshita Haruo, Yuasa Isao, Kishi Koichiro
Abstract excerpt
This study confirms the presence of a novel variable number of tandem repeats polymorphism, designated as HumDN1, in intron 4 of the human deoxyribonuclease I (DNase I) gene. Genotyping was performed without difficulty by PCR-amplification and separation by agarose gel electrophoresis in 423 Japanese, originating from four geographically diverse areas in Japan, and 89 Germans. The HumDN1 allele variability was...
Topics
- DNA Fingerprinting
- Deoxyribonuclease I
- Gene Frequency
- Genetics, Population
- Genotype
- Germany
- Humans
- Introns
- Japan
- Polymorphism, Genetic
- Racial Groups
- Sequence Analysis, DNA
- Tandem Repeat Sequences