Article
Genotyping of human deoxyribonuclease I polymorphism by the polymerase chain reaction.
Electrophoresis - 1 Oct 1995
Yasuda T, Nadano D, Tenjo E, Takeshita H, Sawazaki K, Nakanaga M, Kishi K
Abstract excerpt
We recently completely elucidated the molecular basis of genetic polymorphism in human deoxyribonuclease I and found it to be controlled by four codominant alleles, DNASE1*1, *2, *3 and *4. In this paper we describe a novel DNase I-genotyping system that could be used directly on DNA samples usin...
Topics
- Alleles
- Base Sequence
- Deoxyribonuclease I
- Deoxyribonucleases, Type II Site-Specific
- Exons
- Genotype
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
