Article
The fifth allele of the human deoxyribonuclease I (DNase I) polymorphism.
Electrophoresis - 1 Oct 1997
Iida R, Yasuda T, Aoyama M, Tsubota E, Kobayashi M, Yuasa I, Matsuki T, Kishi K
Abstract excerpt
The fifth allele, DNASE1*5, of human deoxyribonuclease I (DNase I) has been discovered. Polymerase chain reaction fragments containing exon 5 of the DNase I gene were screened for DNA polymorphism using single-strand conformation polymorphism (SSCP) analysis. DNAs from 114 unrelated Japanese and...
Topics
- Alleles
- Deoxyribonuclease I
- Exons
- Genotype
- Heterozygote
- Humans
- Isoelectric Focusing
- Isoenzymes
- Mutation
- Nucleic Acid Conformation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational
- Sequence Analysis, DNA