Article
Deoxyribonuclease I gene polymorphism in Han Chinese population: frequency and effect on glucose and lipid parameters.
Molecular biology reports - 1 Sept 2008
Ni Yuhua, Zhang Jianjun, Sun Baogui
Abstract excerpt
DNASE1, the encoding gene of deoxyribonuclease I (DNase I), exhibits polymorphisms, including a single nucleotide polymorphism (SNP A2317G) in exon 8 and a 56 bp variable number of tandem repeat, designated as HumDN1 in intron 4. Several different ethnic population studies have revealed both A2317G and HumDN1 demonstrate genetic heterogeneity in the worldwide distribution. Recently, G2317 allele was proposed as...
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