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Article

Analysis of limb patterning in BMP-7-deficient mice.

Developmental genetics - 1 Jan 1996

Hofmann C, Luo G, Balling R, Karsenty G

Abstract excerpt

Bone morphogenetic proteins (BMPs) are polypeptide signaling molecules, belonging to the TGF-beta superfamily. They were originally identified by their ability to induce ectopic bone formation, but their expression patterns in embryos suggest multiple functions. BMP-7-deficient mice show among other mesodermal and skeletal patterning defects, polydactyly in the hindlimbs [Luo G, Hofmann C, Bronckers ALJJ, Sohocki...

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Identifiers

PMID: 8792608
DOI: 10.1002/(SICI)1520-6408(1996)19:1<43::AID-DVG5>3.0.CO;2-0

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