A duplicated zone of polarizing activity in polydactylous mouse mutants.

doi:10.1101/gad.9.13.1645

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Article

A duplicated zone of polarizing activity in polydactylous mouse mutants.

Genes & development - 1 Jul 1995

Masuya H, Sagai T, Wakana S, Moriwaki K, Shiroishi T

Abstract excerpt

The positional signaling along the anteroposterior axis of the developing vertebrate limb is provided by the zone of polarizing activity (ZPA) located at the posterior margin. Recently, it was established that the Sonic hedgehog (Shh) mediates ZPA activity. Here we report that a new mouse mutant,...

Topics

Animals
Bone and Bones
Chromosome Mapping
Crosses, Genetic
Embryonic Induction
Female
Fibroblast Growth Factor 4
Fibroblast Growth Factors
Gene Expression
Genes, Homeobox
Genetic Linkage
Hedgehog Proteins
Heterozygote
Homozygote
In Situ Hybridization
Male
Mice
Mice, Inbred C57BL

Source

Open in PubMed

Identifiers

PMID: 7628698
DOI: 10.1101/gad.9.13.1645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7628698-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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