Article
Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice.
Developmental genetics - 1 Jan 1998
Katagiri T, Boorla S, Frendo J L, Hogan B L, Karsenty G
Abstract excerpt
Analysis of the skeletal phenotypes caused by the genetic inactivation of individual Bmps, along with the study of their expression patterns, suggest possible functional redundancy of these molecules. To investigate the effect on skeleton development of the combined absence of some Bmp genes expr...
Topics
- Animals
- Bone Morphogenetic Protein 2
- Bone Morphogenetic Protein 4
- Bone Morphogenetic Protein 5
- Bone Morphogenetic Protein 7
- Bone Morphogenetic Proteins
- Bone and Bones
- Heterozygote
- Limb Deformities, Congenital
- Mice
- Mice, Mutant Strains
- Phenotype
- Ribs
- Transforming Growth Factor beta