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Article

Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.

The Korean journal of internal medicine - 1 Jul 1994

Koh K C, Lee H S, Kim C Y

Abstract excerpt

OBJECTIVES: It has been controversial whether or not the emergence of precore mutant HBV is related to the severe form of chronic hepatitis B (CH-B). To further clarify the role of the precore mutant HBV in the natural course of CH-B, we conducted a longitudinal analysis of precore-region sequences according to the biochemical severity along with seroconversion to anti-HBe in patients with CH-B. METHODS: The...

Topics

Adult
Amino Acid Sequence
DNA, Viral
Female
Hepatitis B
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis, Chronic
Humans
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 7865490
DOI: 10.3904/kjim.1994.9.2.61
PMCID: PMC4532063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7865490-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.PMID 7865490Read ↗

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