Article
Functional specificity of Hoxa-4 in vertebral patterning lies outside of the homeodomain.
Proceedings of the National Academy of Sciences of the United States of America - 3 Sept 1996
Sreenath T L, Pollock R A, Bieberich C J
Abstract excerpt
The Hox family of proteins plays a central role in establishing the body plan of a wide range of metazoan organisms. Each member of this family of transcriptional regulators has a distinct functional specificity, yet they bind to similar DNA target sequences through their conserved homeodomain. T...
Topics
- Animals
- Animals, Newborn
- Base Sequence
- Cytoskeletal Proteins
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Molecular Sequence Data
- Phenotype
- Proteins
- Substrate Specificity
- Transgenes