Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.

doi:10.1006/dbio.1996.0137

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Article

Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.

Developmental biology - 15 Jun 1996

Zákány J, Gérard M, Favier B, Potter S S, Duboule D

Abstract excerpt

Hoxa-11 and Hoxd-11 are paralogous genes required for proper development of the vertebral column, the limbs, and the urogenital system. To further explore the functional relationship between these genes, as well as the potential rescue of one function by the other, we have introduced a Hoxd-11-ex...

Topics

Animals
Female
Genes, Homeobox
Homeodomain Proteins
Lumbar Vertebrae
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Transgenic
Mutation
Phenotype
Transcription Factors

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