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Article

Identification and mapping of Mendelian subtypes of disease.

Genetic epidemiology - 1 Jan 1995

Vieland V J, Mérette C, Goodman D, Rouillard E

Abstract excerpt

We took as our working hypothesis the premise that there could be a single locus of major effect underlying a subset of cases in the simulated Problem 2 data set, and took as our primary goal the task of mapping that locus. Treating the disease as dichotomous and using discriminant function analysis, we were able to separate affected individuals into two disease categories: Disease Type I (DT-I) cases, whose...

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PMID: 8788015
DOI: 10.1002/gepi.1370120648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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