Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of interleukin-1 receptor antagonist in Type 1 diabetic children.

Pediatric research - 1 May 2022

Abed Neveen T, Ramadan Ismail A, Mohammed Shuzan A, El-Shanawany Eman M

Abstract excerpt

BACKGROUND: Interleukin-1 receptor antagonist (IL1RN) variable number tandem repeats (VNTRs) are not fully understood in Type 1 diabetes mellitus (T1DM). It may affect IL1RN level and modify the disease risk. We aimed to study IL1RN VNTR polymorphism in Egyptian children with T1DM to clarify its potential role as a risk factor for T1DM and its effect on plasma IL1RN level. METHODS: A case-controlled study...

Topics

Join the communities discussing this publication.

Child
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Genotype
Interleukin 1 Receptor Antagonist Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Minisatellite Repeats

Polymorphism, Genetic

Source

Identifiers

PMID: 34002010
DOI: 10.1038/s41390-021-01569-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of interleukin-1 receptor antagonist in Type 1 diabetic children.PMID 34002010Read ↗

A novel association between IL1-Ra (receptor antagonist) gene polymorphism and T1DM in Al-Madina Al-Mounawra.Semantic proximity Read ↗

Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: a study in the north Indian population.Semantic proximity Read ↗

Genetic association of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86 bp repeat) polymorphisms with Type 2 diabetes mellitus in North Indians.Semantic proximity Read ↗

Genetic association between interleukin-10 gene rs1518111 and rs3021094 polymorphisms and risk of type 1 diabetes and diabetic nephropathy in Egyptian children and adolescents.Semantic proximity Read ↗

Relationship Between Polymorphisms of Interleukin-1 Receptor Antagonist (IL-1Ra) Genes and Susceptibility to Systemic Lupus Erythematosus in Iranian Population.Semantic proximity Read ↗

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits.Semantic proximity Read ↗

The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs).Semantic proximity Read ↗

Genetic associations of IL1RN polymorphisms with metabolic syndrome in a Korean population.Semantic proximity Read ↗

Polymorphisms in the interleukin-6 receptor gene (Asp358Ala) and body mass index in Chilean women with type 1 diabetes.Semantic proximity Read ↗

Polymorphisms of interleukin 1 gene IL1RN are associated with Tourette syndrome.Semantic proximity Read ↗

The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population.Semantic proximity Read ↗

Vitamin D receptor gene polymorphisms in Sudanese children with type 1 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.