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Article

Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes.

Diabetes - 1 Dec 2002

Marculescu Rodrig, Endler Georg, Schillinger Martin, Iordanova Nelly, Exner Markus, Hayden Evelyn, Huber Kurt, Wagner Oswald, Mannhalter Christine

Abstract excerpt

Recently, inflammation has received considerable attention in the pathogenesis of both type 2 diabetes and atherosclerosis. The interleukin-1 receptor antagonist (IL-1ra) is a major modulator of the interleukin-1 pro-inflammatory pathway. We studied the relationship between a variable number tandem repeat (VNTR) polymorphism in intron 2 of the IL-1ra gene (IL1RN) and coronary artery disease (CAD) in patients with...

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Source

Identifiers

PMID: 12453918
DOI: 10.2337/diabetes.51.12.3582

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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