Article
Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: a study in the north Indian population.
Indian journal of medical sciences - 1 Jul 2008
Bid Hemant Kumar, Konwar Rituraj, Agrawal C G, Banerjee Monisha
Abstract excerpt
BACKGROUND: Inflammation is a key event closely associated with the pathophysiology of type 2 diabetes mellitus (T2DM). Association of genetic polymorphisms of inflammatory cytokines with T2DM is largely unknown. Our objective was to investigate the relationship of polymorphism of IL-1RN and IL-4, two important biomarkers of inflammation, with the risk of T2DM. SETTING AND DESIGN: We recruited 120 clinically...
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