Article
Human T cell lymphotropic retroviruses: association with diseases of the nervous system.
Intervirology - 1 Jan 1997
Kitze B, Brady J N
Abstract excerpt
In less than 1% of persistently infected individuals, human T cell lymphotropic virus type I (HTLV-I) causes a chronic inflammatory disease of the central nervous system (CNS), called HTLV-I-associated myelopathy/tropical spastic paraparesis. Important prerequisites for disease induction are oligoclonal expansion of HTLV-I-infected CD4+ T lymphocytes, their trafficking across the blood-brain barrier, expression...
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