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Article

A Saccharomyces cerevisiae mutant defines a new locus essential for resistance to the antitumour drug bleomycin.

Canadian journal of microbiology - 1 Aug 1996

Ramotar D, Masson J Y

Abstract excerpt

The antitumor drug bleomycin can produce a variety of lesions in the cellular DNA by a free radical dependent mechanism. To understand how these DNA lesions are repaired, bleomycin-hypersensitive mutants were isolated from the yeast Saccharomyces cerevisiae. We report here the analysis of one mutant, DRY25, that showed extreme sensitivity to bleomycin. This mutant also exhibited hypersensitivity to hydrogen...

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Identifiers

PMID: 8776853
DOI: 10.1139/m96-105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Saccharomyces cerevisiae mutant defines a new locus essential for resistance to the antitumour drug bleomycin.PMID 8776853Read ↗

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