Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.

Mutation research - 1 Mar 2012

Grogan Dennis, Jinks-Robertson Sue

Abstract excerpt

Although DNA-protein cross-links (DPCs) pose a significant threat to genome stability, they remain a poorly understood class of DNA lesions. To define genetic impacts of DPCs on eukaryotic cells in molecular terms, we used a sensitive Saccharomyces cerevisiae frameshift-detection assay to analyze mutagenesis by formaldehyde (HCHO), and its response to nucleotide excision repair (NER) and translesion DNA synthesis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to DNA-Directed DNA Polymerase
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

Share to Formaldehyde

Share to Mutagenesis

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22197481
DOI: 10.1016/j.mrfmmm.2011.12.004
PMCID: PMC3591480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.PMID 22197481Read ↗

Multiple DNA repair pathways prevent acetaldehyde-induced mutagenesis in yeastSemantic proximity Read ↗

Dissecting Highly Mutagenic Processing of Complex Clustered DNA Damage in Yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivitySemantic proximity Read ↗

DNA damage-processing pathways involved in the eukaryotic cellular response to anticancer DNA cross-linking drugs.Semantic proximity Read ↗

MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutationsSemantic proximity Read ↗

Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitive Single-Stranded DNA Reporter System in Budding Yeast.Semantic proximity Read ↗

Genome-wide mutation spectra of canonical and atypical UV photoproducts in S. cerevisiae.Semantic proximity Read ↗

The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress.Semantic proximity Read ↗

Methylglyoxal mutagenizes single-stranded DNA via Rev1-associated slippage and mispairingSemantic proximity Read ↗

The pso mutants of Saccharomyces cerevisiae comprise two groups: one deficient in DNA repair and another with altered mutagen metabolism.Semantic proximity Read ↗

The effect of oxidative metabolism on spontaneous Pol zeta-dependent translesion synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

DNA damage bypass pathways and their effect on mutagenesis in yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.