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Article

Genetic control of cuticle formation during embryonic development of Drosophila melanogaster.

Genetics - 1 May 2002

Ostrowski Stephen, Dierick Herman A, Bejsovec Amy

Abstract excerpt

The embryonic cuticle of Drosophila melanogaster is deposited by the epidermal epithelium during stage 16 of development. This tough, waterproof layer is essential for maintaining the structural integrity of the larval body. We have characterized mutations in a set of genes required for proper deposition and/or morphogenesis of the cuticle. Zygotic disruption of any one of these genes results in embryonic...

Topics

Amino Acid Sequence
Animals
Benzamides
Cadherins
Chitin
Chitin Synthase
Chromosome Mapping
Drosophila melanogaster
Gene Expression Regulation, Developmental
Molecular Sequence Data
Mutation

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Sequence Alignment

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Identifiers

PMID: 12019232
DOI: 10.1093/genetics/161.1.171
PMCID: PMC1462094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12019232-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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