Article
Functional dissection of the Drosophila Kallmann's syndrome protein DmKal-1.
BMC genetics - 11 Oct 2006
Andrenacci Davide, Grimaldi Maria R, Panetta Vittorio, Riano Elena, Rugarli Elena I, Graziani Franco
Abstract excerpt
BACKGROUND: Anosmin-1, the protein implicated in the X-linked Kallmann's syndrome, plays a role in axon outgrowth and branching but also in epithelial morphogenesis. The molecular mechanism of its action is, however, widely unknown. Anosmin-1 is an extracellular protein which contains a cysteine-rich region, a whey acidic protein (WAP) domain homologous to some serine protease inhibitors, and four...
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