Article
MHox and vertebrate skeletogenesis: the long and the short of it.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Sept 1995
Brickell P M
Abstract excerpt
The development of the vertebrate skeleton is under complex genetic control, and good progress is being made towards identifying the genes responsible. A recent paper contributes to this progress by describing transgenic mice in which the homeobox-containing MHox gene has been disrupted. MHox(-/-) mice have a range of skeletal defects, involving loss or shortening of structures in the skull, face and limb....
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