What do BMPs do in mammals? Clues from the mouse short-ear mutation.

doi:10.1016/0168-9525(94)90014-0

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Article

What do BMPs do in mammals? Clues from the mouse short-ear mutation.

Trends in genetics : TIG - 1 Jan 1994

Kingsley D M

Abstract excerpt

Bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that were originally isolated on the basis of their remarkable ability to induce the formation of ectopic bones when implanted into adult animals. The first mutations identified in a mammalian BMP gene suggest that me...

Topics

Animals
Bone Development
Bone Morphogenetic Proteins
Growth Substances
Mice
Mice, Mutant Strains
Mutation
Proteins
Signal Transduction

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