Article
The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis.
Molecular and cellular biology - 1 Oct 2010
Liu Wenjin, Watson Spencer S, Lan Yu, Keene Douglas R, Ovitt Catherine E, Liu Han, Schweitzer Ronen, Jiang Rulang
Abstract excerpt
The Mohawk homeobox (Mkx) gene encodes a new atypical homeodomain-containing protein with transcriptional repressor activity. Mkx mRNA exhibited dynamic expression patterns during development of the palate, somite, kidney, and testis, suggesting that it may be an important regulator of multiple developmental processes. To investigate the roles of Mkx in organogenesis, we generated mice carrying a null mutation in...
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