Article
K-ras gene mutation in sputum samples containing atypical cells and adenocarcinoma cells in the lung.
Carcinogenesis - 1 Aug 1996
Shiono S, Omoe K, Endo A
Abstract excerpt
We analyzed the presence or absence of K-ras mutations in sputum samples with atypical cells by colony hybridization. The frequency of K-ras mutations in 104 patients with adenocarcinoma of the lung was also examined using dot blotting. No mutations in K-ras codon 12 were detected in the 12 sputum samples examined, which included three specimens from patients who later developed lung adenocarcinoma. Because of...
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