Article
Genetics and lung carcinoma in Okinawa Prefecture, Japan.
Anticancer research - 1 Jan 2000
Hiroshima K, Toyozaki T, Iyoda A, Fujisawa T, Genka K, Ohwada H
Abstract excerpt
BACKGROUND: Although the incidence of all cancers in Okinawa is the lowest in Japan, that of lung cancer is high. This study was performed to clarify the underlying mechanism of this tendency. MATERIALS AND METHODS: Family histories of the lung cancer patients in Okinawa, p53 mutation, microsatellite alterations, and titers of serum anti-p53 antibodies were examined. RESULTS: The number of patients who had...
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