Article
Loss of heterozygosity on chromosome 1 in human hepatoblastoma.
International journal of cancer - 7 Aug 1996
Kraus J A, Albrecht S, Wiestler O D, von Schweinitz D, Pietsch T
Abstract excerpt
In previous studies we have found loss of heterozygosity (LOH) on chromosome arm 11p in 33% of hepatoblastomas (HBs). In addition, cytogenetic studies have revealed aberrations of chromosome arm 1p in single cases. Therefore, we have used the PCR to amplify 10 microsatellites on the short arm and...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- DNA, Satellite
- Fathers
- Female
- Genetic Markers
- Genomic Imprinting
- Hepatoblastoma
- Humans
- Liver Neoplasms
- Male
- Middle Aged