Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 mutation, allele loss on chromosome 17p, and DNA content in ovarian carcinoma.

The Journal of pathology - 1 Jun 1996

McManus D T, Murphy M, Arthur K, Hamilton P W, Russell S E, Toner P G

Abstract excerpt

The aim of this investigation was to explore the relationships between p53 mutation, DNA aneuploidy, 17p deletions, and clinical stage in ovarian cancer. Nuclear suspensions were obtained by tissue disaggregation, stained with propidium iodide, and analysed on a Coulter EPICS Elite flow cytometer. DNA cell cycle analysis was performed using Multicycle software (Phoenix Flow Systems). DNA extracted from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Heterozygote

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8758210
DOI: 10.1002/(SICI)1096-9896(199606)179:2<177::AID-PATH561>3.0.CO;2-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 mutation, allele loss on chromosome 17p, and DNA content in ovarian carcinoma.PMID 8758210Read ↗

High incidence of p53 gene mutation in human ovarian cancer and its association with nuclear accumulation of p53 protein and tumor DNA aneuploidy.Semantic proximity Read ↗

Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma.Semantic proximity Read ↗

The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma.Semantic proximity Read ↗

Analysis of allelic imbalance on chromosome 17p13 in stage I and stage II epithelial ovarian cancers.Semantic proximity Read ↗

Allelic loss on chromosome 17 in human ovarian cancer.Semantic proximity Read ↗

Allelic deletion on chromosome 17p13.3 in early ovarian cancer.Semantic proximity Read ↗

Somatic DNA alterations in endometriosis: high frequency of chromosome 17 and p53 loss in late-stage endometriosisSemantic proximity Read ↗

Involvement of p53 gene in the allelic deletion of chromosome 17p in human ovarian tumors.Semantic proximity Read ↗

Allele loss from large regions of chromosome 17 is common only in certain histological subtypes of ovarian carcinomas.Semantic proximity Read ↗

Poor correlation with loss of heterozygosity on chromosome 17p and p53 mutations in ovarian cancers.Semantic proximity Read ↗

Allelic loss in ovarian cancer.Semantic proximity Read ↗

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.