Article
Replication infidelity during a single cycle of Ty1 retrotransposition.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996
Gabriel A, Willems M, Mules E H, Boeke J D
Abstract excerpt
Retroviruses undergo a high frequency of genetic alterations during the process of copying their RNA genomes. However, little is known about the replication fidelity of other elements that transpose via reverse transcription of an RNA intermediate. The complete sequence of 29 independently integrated copies of the yeast retrotransposon Ty1 (173,043 nt) was determined, and the mutation rate during a single cycle...
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