Article
Transcriptional co-activation at the ansB promoters: involvement of the activating regions of CRP and FNR when bound in tandem.
Molecular microbiology - 1 Nov 1995
Scott S, Busby S, Beacham I
Abstract excerpt
Previous work with semi-synthetic promoters containing a single CRP binding site centred at 41.5 bp from the transcription start site has demonstrated enhanced transcription (synergism) when a second binding site, for CRP or FNR, is placed upstream at around -91 bp. The ansB promoter in Escherichia coli is co-activated in a co-dependent manner by one dimer each of CRP and FNR protein whose binding sites are at...
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