Article
Synergistic activation of a human promoter in vivo by transcription factor Sp1.
Molecular and cellular biology - 1 Apr 1991
Anderson G M, Freytag S O
Abstract excerpt
Many eucaryotic promoters contain multiple binding sites for sequence-specific DNA-binding proteins. In some cases, these proteins have been shown to interact synergistically to activate transcription. In this study, we address the possibility that the transcription factor Sp1 can synergistically...
Topics
- Argininosuccinate Synthase
- Base Sequence
- Binding Sites
- Cloning, Molecular
- Deoxyribonuclease I
- Gene Expression
- Gene Expression Regulation
- Humans
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Promoter Regions, Genetic
- Sp1 Transcription Factor
- Transcription, Genetic
- Transfection